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                    Anti-Mouse F4/80 Antigen PE 抗小鼠F4/80抗原PE抗體

                    • 更新時間:  2023-07-24
                    • 產(chǎn)品型號:  eBiosience12-4801-82
                    • 簡單描述
                    • Host
                      Rat
                      Isotype
                      IgG2a, kappa
                      Reactivity
                      Mouse
                      Conjugate
                      PE
                      Laser
                      Blue Laser, Green Laser, Yellow-Green Laser
                      Emit
                      575 nm
                      Excite
                      488 - 561 nm
                      Reported Applications
                      Flow Cytometric Analysis
                    詳細(xì)介紹

                    Also known as: Pan Macrophage Marker

                    Clone: BM8

                    Description: The BM8 monoclonal antibody reacts with mouse F4/80 antigen, an approximay 125 kDa transmembrane protein. The F4/80 antigen is expressed by a majority of mature macrophages and is the best marker for this population of cells. However, other cell types such as Langerhans cells and liver Kupffer cells have been reported to express this antigen. Expression of F4/80 commences during early myeloid development and is upregulated on all BM cells stimulated in vitro with M-CSF. It has been shown that some cytokines downregulate the expression of F4/80 resulting in lack of F4/80 antigen on a subpopulation of macrophages, especially in the lymphoid microenvironment in vivo

                    Host Rat
                    Isotype IgG2a, kappa
                    Reactivity Mouse
                    Conjugate PE
                    Laser Blue Laser, Green Laser, Yellow-Green Laser
                    Emit 575 nm
                    Excite 488 - 561 nm
                    Reported Applications Flow Cytometric Analysis

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